Those who struggle to fall asleep most nights could experience a more rapid decline in memory and thinking skills as they age, increasing their risk of developing dementia, research today suggested.
Studies have long warned that both the quality and amount of sleep can influence the risk of developing the memory-robbing condition.
But now US scientists say that people with chronic insomnia—defined as trouble sleeping at least three days a week for three months—have a 40 per cent higher risk of developing dementia, than those without the sleep disorder.
This is the equivalent of three-and-a-half years of ageing.
Dr Diego Carvalho, a neurologist and sleep medicine expert from the American Academy of Neurology, said: ‘Insomnia doesn’t just affect how you feel the next day—it may also impact your brain health over time.
‘We saw fast decline in thinking skills and changes in the brain that suggest chronic insomnia could be an early warning sign or even a contributor to future cognitive problems.’
In the study, published in the journal Neurology, researches tracked 2,750 cognitively healthy adults with an average age of 70 for just over five years.
Of the cohort, 440 people had been diagnosed with chronic insomnia at the start of the study.
Researchers found that chronic insomnia were 40 per cent more likely to develop dementia or mild cognitive issues than people without the sleep disorder
Participants were asked to rate their sleep at the beginning of the study, highlighting whether they had been sleeping more or less than usual over the past two weeks.
Every year participants were invited back to the lab to complete memory and thinking tests.
Brain scans were also carried out to identify any areas where small vessel disease may have damaged brain tissue—known as white matter hyperintensities—and look for build up of amyloid plaque, a protein which has been linked to Alzheimer’s disease.
During the study, 14 per cent of the participants with chronic insomnia developed mild cognitive impairment or dementia, compared to just 10 per cent—or 231 people—who did not have the sleep disorder.
After accounting for confounding factors—including age, blood pressure, use of sleep medications, and a diagnosis of sleep apnea—they concluded that people with insomnia were 40 per cent more likely to develop mild cognitive impairment or dementia.
Insomnia sufferers also had faster declines of tests measuring different thinking skills.
People with an insomnia diagnosis who reported getting less sleep than usual at the start of the study were also more likely to have lower baseline scores, comparable to being four years older than their chronological age.
They also had more damaged brain tissue and amyloid plaque build up, resembling that of people with the APOE ε4 gene, a known genetic risk factor for the memory-robbing disease.
Unsurprisingly, those with the gene were found to be more vulnerable, showing steeper declines in memory and thinking skills.
‘Our results suggest that insomnia may affect the brain in different ways, involving not only amyloid plaques, but also small vessels supplying blood to the brain,’ Dr Carvalho explained.
‘This reinforces the importance of treating chronic insomnia—not just to improve sleep quality but potentially to protect brain health as we age.
‘Our results also add to a growing body of evidence that sleep isn’t just about rest—it’s also about brain resilience.’
However, the researchers noted that at this point their findings are limited because they were relying on insomnia diagnoses from medical records, rather than conducting their own assessments which could better reflect how severe symptoms were.
They also did not take into consideration undiagnosed cases, which could have a confounding effect.
Last year, a study found that around one in six people in the UK suffer from insomnia, yet 65 per cent never seek help for their problem.
Poor sleep has been linked to a number of health problems, including cancer, stroke and neurodegenerative conditions like dementia.
Around 900,000 Brits are currently thought to have the memory-robbing disorder. But University College London scientists estimate this will rise to 1.7million within two decades as people live longer. It marks a 40 per cent uptick on the previous forecast in 2017
Currently around 944,000 people in the UK are thought to be living with dementia, while the figure is expected to be closer to 7million in the US.
Alzheimer’s, the most common form of the memory-robbing condition affects around 6 in 10 people with dementia. There is currently no cure.
But researchers said today a simple blood test to be offered to thousand of adults could detect Alzheimer’s before the cruel disease takes hold.
In a landmark trial, researchers from University College London will uses tests to detect proteins in the blood linked to dementia in an effort to revolutionise NHS diagnostic rates.
This article was originally published by a www.dailymail.co.uk . Read the Original article here. .